We actively develop computational tools with the Open Chromosome Collective (Open2C).

Open2C repositories under active development include:

  • bioframe: flexible workflows with genomic interval dataframes.
  • cooltools: analysis of chromosome conformation data stored in the cooler format.
  • polychrom: for biophysical models of chromosome folding.

For neural network models of genome folding see:

  • akita: for predicting mammalian interphase genome folding from DNA sequence

Talks and Slides